Therapeutic implications of a molecular link between survivin and telomerase reverse transcriptase

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/568704

Funding Status
Closed

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Funded Activity Summary

A unifying feature of all types of cancer cells is that they are immortal. Our investigations will build upon our recent results that showed the gene survivin is involved in cancer cell immortalisation. We will characterise a molecular link between survivin and the enzyme telomerase, which is central to cancer cell immortality. Furthermore, we will demonstrate the therapeutic potential of turning off both survivin and telomerase as a novel approach to halting the growth of cancer cells.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $547,970.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Oncology And Carcinogenesis

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Cancer and Related Disorders | cancer and related disorders | cancer biology | cellular transformation | immortalisation | telomerase | telomeres

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