Examining the role of profilin as a regulator of cancer aggressiveness

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/568301

Funding Status
Closed

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Funded Activity Summary

Cancer treatment in Australia costs ~ $2.7 billion per annum. Current mainstream treatments often cause major side effects and thus less toxic therapeutic approaches are urgently needed. Profilin has recently emerged as a promising anti-cancer target. We will investigate how cancer can be suppressed by altering the interaction between profilin and its partners (lipids, phosphoinositides, and actin). This project will provide essential groundwork for the development of novel cancer therapeutics.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $261,778.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Oral implantology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Breast cancer metastasis | Cancer | Cancer biology | Cell signalling | Fluorescence spectroscopy and microscopy | Future therapy | Metastasis suppressor | NMR spectroscopy | Protein structure | Protein-phospholipid interaction

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