Investigating the delivery of cytotoxic T cell lytic granules and the microenvironment of the immunological synapse

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/567082

Funding Status
Closed

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Funded Activity Summary

T cells recognise infected or cancer cells and eliminate them from the body. They kill their targets by tightly attaching and releasing toxic proteins, which cause the target to undergo cell suicide. This research will use high resolution imaging to investigate the environment of the synapse between the two cells and understand parameters required for the delivery of a lethal hit. This will provide powerful insights into the working of the cell, and may identify novel intervention targets

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2013

Funding Scheme: Early Career Fellowships

Funding Amount: $355,169.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Clinical chemistry (incl. diagnostics)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Cell Biology | Cell Death-apoptosis | Cytotoxic T cell | Exocytosis | Immune Response

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