Regulation of inflammation and thrombosis by Endothelial Protein C Receptor and Thrombomodulin in xenograft rejection

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/567036

Funding Status
Closed

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Funded Activity Summary

Pig-to-human organ transplantation may be the solution to the human organ shortage crisis. However, cross-species organ transplantation invariably results in graft destruction and rejection. Genetically modified mice expressing anti-rejection proteins will be tested to assess their effects and benefits on grafts. If such genes improve graft outcome, pigs with similar genetic modifications will be generated for the purposes of pig-to-primate organ transplantation studies.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2010

Funding Scheme: NHMRC Postgraduate Scholarships

Funding Amount: $35,085.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Dermatology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

anti-inflammatory | antithrombotic | cell death-apoptosis | murine models | xenotransplantation

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