Protective roles for protease-activated receptor 2 (PAR2) in parasitic and autoimmune diseases

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/566955

Funding Status
Closed

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Funded Activity Summary

Parasite infection has unique and specific effects on the human immune system which can prevent allergy and diseases such as diabetes and multiple sclerosis (MS). We have discovered a drug which can cause the immune system to behave in a similar way to that observed during a parasite infection. This project will explore how the drug mimics a parasite and examine the potential of this treatment to prevent MS using a mouse model of this disease.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $483,421.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical biochemistry - carbohydrates

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Animal models of multiple sclerosis | Autoimmune diseases | G protein-coupled receptors | Hypersensitivity | Immune regulation | Immunotherapy | Multiple sclerosis | Parasite infection | Parasitic infection | Receptor mimetic

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