Vasopressin: a novel target in heart failure

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/566947

Funding Status
Closed

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Funded Activity Summary

Heart failure (HF) is the most common cause of hospital admission in those over 65y, and has significant morbidity and mortality. We need to develop new strategies to treat HF. Plasma vasopressin (AVP) levels are elevated in HF, and may contribute to adverse outcomes. This proposal will assess the utility of blocking the vasopressin V1 and V2 receptors in a rat model of HF. We shall also measure AVP in humans with HF. The results of this work may result in new approaches to treat HF patients.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $573,629.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Nutrigenomics and personalised nutrition

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Aquaresis | Cardiovascular hormones and disease | Fluid and electrolyte disturbance | Heart disease | Heart failure | Heart failure, congestive | Myocardial infarction | Vasopressin and its receptors

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