The impact of influenza A virus PB1-F2 protein on host immunity and the potential for therapeutic targeting

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/566780

Funding Status
Closed

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Funded Activity Summary

The 1918 influenza virus pandemic resulted in 50 million deaths globally and there is potential for new pandemics, such as the predicted H5N1 Bird Flu . Exact causes of such devastating lethality are not fully identified. Newly discovered influenza A virus (IAV) PB1-F2 protein is present in nearly all highly pathogenic IAVs and promotes virus virulence. This study will further examine the way in which PB1-F2 impacts the host, revealing potential therapeutic targets to lessen disease burden.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $317,076.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Infectious Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Immune Response | Influenza | Microbiology-virology | Mucosal Immunity | Mucosal Inflammation | Respiratory virus infection | Viral Immunology | Virus Pathogenesis

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