Characterisation of a newly-discovered, virulence-associated, protein secretion system of enteropathogenic E. coli

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/566770

Funding Status
Closed

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Funded Activity Summary

The cell walls of bacteria act as a barrier to the export of any proteins they produce. We recently discovered a protein secretion system, which diarrhoea-causing strains of E. coli require to cause disease. The aim of this study is to characterise this secretory system, and discover how it functions and what it secretes. The knowledge obtained from this research will shed new light on how E. coli causes disease and could reveal novel methods to treat and prevent infections with this bacterium.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $582,149.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Allergy

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Bacterial pathogenesis | Enteric bacteria | Enteric infections | Enterotoxigenic Escherichia coli | Pathogenic E. coli | Protein secretion

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