Modulation of neurotherapeutic cell signalling pathways by metallo-complexes as a treatment for Alzheimers disease.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/566764

Funding Status
Closed

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Funded Activity Summary

Alzheimer's disease (AD) is an enormous burden on the Australian health care system . We have begun to investigate therapeutic treatments based on triggering protective cell signalling pathways with metal-based compounds. These compounds trigger the activation of a signalling cascade resulting in inhibition of AD-associated symptoms. In this proposal we will further investigate how these compounds modulate specific receptors and cellular kinase activity to protect neurons in the AD brain.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $653,113.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Therapies And Therapeutic Technology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Ageing | Alzheimer's disease | Cell signalling | Copper transport | Metal metabolism | Neurodegeneration | Therapeutics

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