Deciphering the Neuroprotective Mechanism of Parkinsons Disease-Associated Protein Kinase PINK1

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/566751

Funding Status
Closed

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Funded Activity Summary

Parkinson's disease is caused by premature death of nerve cells that control body movements. The enzyme PINK1 protects against nerve cell death by chemically modifying specific cellular proteins that maintain cell survival. We aim at identifying these proteins and investigating how PINK1-catalysed modification modulates their ability to maintain nerve cell survival. The study will benefit development of drugs that protect against nerve cell death for treatment and prevention of the disease.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $547,994.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical infection agents (incl. prions)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Mitochondria | Neuronal death | Parkinson'a disease | Parkinson's disease | Pathogenic mechanism | Protein kinases | degeneartive disease of the CNS | neurodegeneration | neurodegenerative diseases | oxidative stress and apoptosis

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