Control of Salvador-Warts-Hippo Pathway activity in Drosophila and mammals

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/566700

Funding Status
Closed

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Funded Activity Summary

The primary function of the Salvador-Warts-Hippo (SWH) pathway is to dictate the appropriate size of organs in developing animals. Deregulation of this pathway results in vastly overgrown organs and can lead to the formation of cancer in humans. Our study will provide important insights into how the size of organs are controlled during development by identifying new SWH pathway components. We will also increase understanding of diseases that arise due to aberrant tissue growth, such as cancer.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $514,048.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cell Development (Incl. Cell Division And Apoptosis)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Drosophila melanogaster | cancer and related disorders | cancer biology | development | growth | organogenesis | signal transduction | tumour supressor genes

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