The Role of NKT cell subsets in the regulation of Experimental Autoimmune Encephalomyelitis

Funding Activity

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Funded Activity Summary

Multiple Sclerosis (MS) is the most common cause of paralysis in young people. EAE is an animal model of MS that recapitulates many features of the human disease. Recent data shows that EAE is mediated by IL-17 producing self-reactive T cells. NKT cells are a group of T cells, whose activation protects against EAE, in an as yet unidentified manner. These studies will provide critical information on the way in which NKT cells regulate immunity and will enhance development of therapies for MS.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2010

Funding Scheme: Career Development Fellowships

Funding Amount: $142,717.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Emergency medicine

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

autoimmune diseases | cytokine | immune regulation | lymphocyte | multiple sclerosis