Experience-dependent maturation and plasticity of the cerebral cortex mediating schizophrenia-like endophenotypes

Funding Activity

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Funded Activity Summary

We will use genetic mouse models of schizophrenia to understand how specific abnormal behaviours are caused, focusing on cells and molecules within the brain. We will investigate how the gene mutations disrupts communication between, and production of, brain cells (neurons), and the role of mental and physical activity. The results of this project will not only have implications for understanding schizophrenia, but also for other brain disorders involving cognitive problems, such as dementia.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $384,199.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical infection agents (incl. prions)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

adult neurogenesis | behaviour | cognitive disorders | gene-environment interactions | molecular neuroscience | neurodevelopmental disorders | psychiatric disorders | psychosis | schizophrenia | synaptic plasticity