The intracellular replicative niche of Legionella species and Coxiella burnetii.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/566568

Funding Status
Closed

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Funded Activity Summary

This project will study how the bacterium that causes Legionnaire's disease survives and grows inside human cells. We have identified new bacterial proteins that allow Legionella to manipulate the normal host cell processes involved in killing an invading bacterium. Similar proteins are also present in the closely related organism, Coxiella, which causes Q-fever. By determining how these proteins act, this work may result in new treatments for Legionnaire's disease and related infections.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $529,632.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Allergy

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Acute respiratory infection | Bacterial pathogen | Host-pathogen interactions | Legionella | Lung inflammation | Pneumonia | macrophage

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