The mechanisms of the anabolic actions of androgens in bone.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/566503

Funding Status
Closed

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Funded Activity Summary

Androgens (male sex hormones) are one of the few agents that increase bone formation. Androgens act by binding to a specific protein, the androgen receptor (AR). To understand exactly how androgens increase bone formation, we will study mice in which the AR is inactivated only in bone forming cells at specific stages of their development. Understanding the way in which androgens act on bone to increase size and strength will be of great benefit in the design of new treatments for osteoporosis.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $470,960.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Nutritional science

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Androgen | Androgens | Animal Model | Bone | Bone Formation | Cre-lox Knockout Mice | Metabolic Bone Diseases | Osteoblast | Osteoporosis | Preventing age-related bone loss

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