The role of voltage-gated Na+ and Ca2+ channels in post-inflammatory hyperexcitability of enteric neurons

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/566502

Funding Status
Closed

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Funded Activity Summary

Gastrointestinal inflammation causes changes in neurons that control gut functions (motility and secretion). These changes in neuronal properties lead to the development of post-inflammatory motility disorders. This will be the first detailed study of neuronal ion channels that are changed after inflammation in the gut. Our study will open the way to the development of therapeutic agents to treat post-inflammatory IBS and other conditions that involve disorders of motility.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $520,000.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical bacteriology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Enteric infections | Enteric nervous system | Gastrointestinal inflammation | Intestinal motility disorders | Ion channels | Irritable Bowel Syndrome

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