Intra- and intercellular spreading in Shigella pathogenesis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/565377

Funding Status
Closed

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Funded Activity Summary

Each year Shigella flexneri bacteria cause over 167 million episodes of dysentery and over 1 million deaths worldwide, under conditions of poor sanitation, in both developed and developing countries. No vaccines are available, and resistance to antibiotics is common. This project will study the a key part of the machinery that allows bacteria use to cause disease, and also to identify drugs that block the machinery which can in future be used to treat infection by these bacteria.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2009

Funding Scheme: NHMRC Project Grants

Funding Amount: $216,318.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Autoimmunity

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Bacillary dysentery | Diarrhoea | Enteric infection | Fever | actin based motility | autotransporter | bacterial pathogen | molecular biology | viruelence factor

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