Involvement of interstitial cells of Cajal in the pathogenesis of diabetic gastroparesis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/565319

Funding Status
Closed

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Funded Activity Summary

Diabetics commonly suffer from gastrointestinal symptoms such as bloating and nausea. We have preliminary evidence that interstitial cells of Cajal (ICC), which are essential for normal gut motility, are particularly vunerable to damage in diabetes. The goal of this study is to determine how the loss of ICC in diabetes leads to delayed gastric emptying. Our overall aim is to identify potential therapeutic targets for improved treatment of diabetes-related gastrointestinal motility disorders.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $386,104.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Sport and exercise nutrition

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

diabetes | digestion | enteric nervous system | gastric motility | gastroenterology | intercellular communication | neuroeffector transmission | obesity | type 2 diabetes

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