Functional validation of FoxP3 target genes in human regulatory T cells

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/565314

Funding Status
Closed

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Funded Activity Summary

Using DNA based technologies we have focused on rare white blood cells known as regulatory T cells. These cells are policeman of the immune system and are responsible for maintaining balanced immune reactions, and preventing attack against harmless substances. These cells prevent autoimmune disease in healthy individuals, and only by first understanding how they work normally can we investigate and correct the defects in autoimmune diseases such as type 1 diabetes.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $545,341.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Gene Expression

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

FoxP3 | Gene Expression | Transcription factors | autoimmune disease | gene discovery | microarray | molecular basis of disease | t cell subsets | tolerance

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