A novel cytokine-receptor survival axis in chronic myeloid leukaemia

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/565204

Funding Status
Closed

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Funded Activity Summary

Cancer cells grow and survive in an unrestrained manner. Current therapies target cancer growth, however they permit the long-term survival of some cancer cells and increase the possibility of drug resistance and disease relapse. We have identified a new molecular switch that is constitutively activated (unregulated) in leukemia. Targeting specific components of this unregulated cell survival may provide new and improved approaches for the development of therapeutics in the treatment of leukemia

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $424,731.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Protein Targeting And Signal Transduction

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cell signalling | cell survival | chronic myeloid leukaemia | cytokine receptor | cytokine signalling | cytokines | growth factors-receptors | leukaemia | phosphorylation | signal transduction

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