The Role of Tau in Experimental Retinal and Optic Nerve Pathology: Relevance to Glaucoma

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/565202

Funding Status
Closed

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Funded Activity Summary

Aberrant processing of the axonal protein, tau, is believed to underlie key pathological events in Alzheimer's Disease (AD). Recent data have suggested a link between AD pathology and retinal neuron death in glaucoma. We have further evidence that changes in tau also occur in models of retinal damage. We thus aim to characterise the role of tau in retinal injury models and to relate these findings to glaucoma with a view to having a greater understanding of this disease process.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $375,225.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical infection agents (incl. prions)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Axonopathy | Excitotoxicity | Glaucoma | Ischaemia-Reperfusion | Neurodegeneration | Optic nerve disease | Retina | Retinal degeneration | Vision disorders-blindness

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