Mechanism of Flightless I function in burn injury and scar formation

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/565004

Funding Status
Closed

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Funded Activity Summary

Extensive scarring is a major clinical problem often resulting from burn injuries. We have previously shown that the cytoskeletal protein, Flightless I (FliI), is an important regulator of wound repair. We now plan to investigate whether FliI is also be the mechanistic link between cytoskeletal remodelling and induction of TGF-betas post-wounding leading to scar formation.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $545,216.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Food properties (incl. characteristics and health benefits)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Burns | Flightless I | Injury | Scar formation | Scar from burns and other trauma | Scarring | TGF-beta | Wound Healing | cytoskeleton

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