Evaluation of a novel antiosteolytic agent: potential in breast-to-bone metastasis and mechanism of action

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/559027

Funding Status
Closed

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Funded Activity Summary

In breast cancer the spread of cancer (metastasis) to bone occurs frequently and causes significant problems including pain, fracture, immobility and paralysis. We have recently discovered that a drug, widely used in Japan and Korea for skin disorders, inhibits breast cancer growth in bone using animal model systems of this disease. This is a very exciting and novel finding. We will further investigate the potential of this drug and identify precisely how it works at the molecular level.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $352,583.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry And Cell Biology Not Elsewhere Classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Breast cancer | Metastasis | Women's health | cancer metastasis | cancer therapy | cancer-induced osteolysis

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