A novel mode of cytokine receptor assembly and activation: functional and structural characterization

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/559001

Funding Status
Closed

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Funded Activity Summary

This proposal will study a group of protein hormones and their receptors, implicated in blood cell cancers and inflammatory diseases and for which current treatments are inadequate. We will determine the mechanism of receptor activation and in particular will seek to link different forms of receptor assembly to different functions. This information will help us develop new drugs with more specificity for certain hormone functions and thus less side effects

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $621,322.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Oral and maxillofacial surgery

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Allergy | Cancer | GM-CSF | Inflammation | Leaukaemia | Protein structure | X-ray crystallography | cytokine receptor | drug design

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