Kallikrein proteases have key functional roles in peritoneal invasion and chemoresistance in epithelial ovarian cancer

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/553045

Funding Status
Closed

Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the .

Funded Activity Summary

Only 30% of ovarian cancer patients with advanced disease survive for 5 years. This is because the cancer quickly spreads into the abdominal cavity and often becomes resistant to chemotherapy. We aim to use a new 3D culture system, mouse models and novel inhibitors to study the roles of 4 kallikrein enzymes in these events. The outcomes from this study will lead to a better understanding of the role of kallikreins in ovarian cancer and may lead to new treatment approaches.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $815,541.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Nutritional science

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Disease Progression | Hormone Dependent Cancers | Invasion and Metastasis | Matrix Proteins | Ovarian Cancer | Proteases and Ovarian Cancer Spread | Serine Proteases- Kallikreins | Womens Health

Related Links