Analysis of the Plasmodium falciparum M18 aspartyl aminopeptidase

Funding Activity

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Funded Activity Summary

Malaria remains a major cause of death and disease in many parts of the world. There is widespread resistance to all currently used drugs and an urgent need for new treatmants. We have identified the malaria enzyme, aspartyl aminopeptidase as a new drug target. This proposal will investigate the biological role of this enzyme and has the potential to identify new compounds which may be effective antimalarial drugs.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $613,683.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Humoural immunology and immunochemistry

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Antimalarial | Enzyme structure | Gene targetting | Malaria control | P.falciparum | Tropical disease | drug design