The complementary effects of matrilins and WARP on chondrogenesis through TGF-beta signaling

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/546505

Funding Status
Closed

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Funded Activity Summary

Osteoarthritis (OA), characterized by degeneration of articular cartilage matrix structure, is one of the most common types of arthritis. Although it is known that aging is a leading factor, the exact cause of degeneration of articular cartilage is not well understood. In order to aid the discovery of treatments and diagnostic tools for this joint disease, understanding functional and mechanistic properties of cartilage specific proteins, namely matrilins and WARP, is essential.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2013

Funding Scheme: Early Career Fellowships

Funding Amount: $327,428.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Interactions (Incl. Adhesion, Matrix, Cell Wall)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

chondrogenesis | extracellular matrix proteins | growth factor signaling | protein assembly | protein interactions

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