Changes to the structure of the centromere during differentiation and cancer progression

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/546454

Funding Status
Closed

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Funded Activity Summary

Every human has 46 chromosomes. Chromosomes are structures that carry genes in all our cells. The centromere is an essential component of a chromosome which governs the process of cell division and segregation of chromosomes. Defects in centromere function cause defects in cell division, which in turn are the cause of various genetic diseases including cancer. We propose to investigate the structure of the centromere and the way in which it changes during cellular differentiation and cancer.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $511,294.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Genome Structure

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cancer | centromeres | chromosome anomolies | chromosomes | differentiation | gene expression | genetic defects | stem cells

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