Gastrokine 2: a novel stomach-specific tumour suppressor gene

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/546430

Funding Status
Closed

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Funded Activity Summary

We will evaluate how a natural protein called gastrokine 2 acts to prevent cancer from developing in the stomach. We will show how gastrokine 2 interacts with another stomach protein TFF1, to block the effects of the inflammatory and cancer causing bacterium Helicobacter pylori, and the way that this bacterium circumvents this by turning off the production of gastrokine 2. Finally a drug which inhibits stomach tumour growth by turning on gastrokine 2 will be tested.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $342,735.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Sport and exercise nutrition

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

STAT3 | gastroenterology | gastrokines | stomach | stomach cancer | tumour growth inhibition | tumour suppressor

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