Novel Candidate Genes, Lung Function and Allergic Airways Disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/546428

Funding Status
Closed

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Funded Activity Summary

We propose to study airway remodelling (structural changes to the airway) and in asthma using human samples and rodent models of asthma. We are particularly interested in investigating the role of trefoil peptide 2 and relaxin, two genes identified as determining lung function. To do this we need to understand the mechanisms of airway remodelling and its impact on disease severity in the patient. A strength of this study is availability of samples from a large study of human asthma.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $581,892.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Respiratory Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

airway disease | airway function | airway remodelling | asthma | asthma therapy | fibrosis | peptides | relaxin | trefoil peptides

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