Lymph Node Stromal Cells: Phenotype, Function and the Induction of Tolerance

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/546259

Funding Status
Closed

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Funded Activity Summary

Autoimmune diseases, where the immune system kills our own tissue, are initiated in lymph nodes. Lymph node structural cells, called fibroblastic reticular cells (FRC), kill white blood cells capable of reacting against the body's own proteins. FRC could be used to prevent diseases like type I diabetes, but little is understood about their actions. We propose to study the way they work and their potential to prevent or treat autoimmunity when transplanted in mice.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2014

Funding Scheme: Early Career Fellowships

Funding Amount: $340,550.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Clinical chemistry (incl. diagnostics)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Autoimmunity | Lymph node | Stromal cells | Tolerance induction | Type 1 diabetes

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