Regulation of pilus biogenesis in Neisseria

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/546004

Funding Status
Closed

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Funded Activity Summary

A group of bacteria called Neisseria cause human-specific infections. To initiate infection, the bacteria must produce a hair-like surface structure, the pilus. The pilus consists mainly of a protein called pilin, and we now understand how pilin production is controlled. However 20 other genes are also involved in pilus production. This project aims to understand how these other genes are controlled and coordinated to assemble this structure that is central to the ability to cause disease.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $280,400.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Allergy

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

adherence | gene regulation | gonorrhoea | meningitis | meningococcal disease | neisseria gonorrhoeae | neisseria meningitidis | pelvic inflamatory disease | septicemia | virulence

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