MTMR4, a regulator of PtdIns(3)P

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/545989

Funding Status
Closed

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Funded Activity Summary

Normally cells only divide when they receive a stimulus from a hormone or growth factor. The PI3-kinase pathway responds to these stimuli and has been implicated in cellular immunity as well as cancer which occurs when cells divide uncontrollably and invade surrounding tissues. We have identified a putative oncogene (cancer causing gene) called MTMR4 that appears to regulate cell growth-invasion and pathogen invasion of immune cells. We aim to characterise the role of MTMR4 in these systems.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $602,673.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Membrane Biology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Breast cancer | Innate immunity | Mechanisms of growth invasion and metastasis | Phagocytosis | Protein Trafficking | breast cancer | confocal microscopy | phospholipids-phosphatase

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