Alteration of glucose metabolism by GPCR activation

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/545952

Funding Status
Closed

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Funded Activity Summary

In type 2 diabetes the effect of insulin to stimulate glucose transport in fat cells and skeletal muscle is impaired so there is great interest in identifying insulin-independent mechanisms that increase glucose transport. Several G protein-coupled receptors (GPCRs) regulate glucose transport independently of insulin but the mechanisms involved in these effects are largely unknown. This project investigates how GPCRs regulate glucose homeostasis and will evaluate them as potential treatments.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2016

Funding Scheme: Career Development Fellowships

Funding Amount: $444,796.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical biochemistry - carbohydrates

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

AMP-activated protein kinase | Adrenergic receptor | G protein-coupled receptors | Pharmacology | Signalling pathways

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