Virulence mechanisms in hypervirulent epidemic strains of Clostridium difficile.

Funding Activity

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Funded Activity Summary

The bacterium Clostridium difficile is the major cause of nosocomial diarrhoea in many countries, including Australia. More virulent isolates have emerged since 2000, leading to increased incidence and severity of disease in many countries and resulting in epidemics. This project will make a major contribution to our understanding of how these bacteria cause disease and may help to prevent outbreaks of the hypervirulent strains in Australia by identifying potential new vaccine candidates.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $499,135.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Allergy

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Antibiotic associated diarrhea | Bacterial Pathogenesis | Bacterial Toxins | Bacterial virulence mechanisms | Clostridium difficile | Clostridium difficile-associated disease | Microbial Genetics | Nosocomial diarrhea