Investigation of a New Rheology Dependent Platelet Aggregation Mechanism

Funding Activity

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Funded Activity Summary

We plan to examine a new mechanism promoting blood clot formation that involves the clumping (aggregation) of blood platelets. Our central hypothesis is that disturbances of blood flow, as occurs in diseased arteries, activates this clotting mechanism through a unique platelet activation process. Defining this new activation mechanism has the potential to lead to new approaches to prevent blood clot formation in patients with heart disease.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $509,447.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Haematology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Cell signalling | Platelet biology-physiology | Thrombosis | atherosclerosis | blood clotting | blood rheology | cell adhesion mechanisms | cell signalling | thrombosis and haemostasis | vascular disease