Investigation of a new platelet contractile mechanism regulating thrombus stability

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/545848

Funding Status
Closed

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Funded Activity Summary

Platelets are small blood cells that form clots to stop bleeding. We have found a new contraction process that causes tight packing of platelets in a clot, enabling the clot to avoid detachment under blood flow. We will study this process and explore the possibility that its inhibition may provide a new way in which to loosen clots, promoting their removal. These studies will provide new insight into clot stability, and may provide clinical benefit in the delivery of clot dissolving agents .

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $499,670.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Haematology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Atherosclerosis | Platelets | Signal transduction | Thrombolysis | Thrombosis | Thrombosis and Haemostasis | Thrombus contraction

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