Regulation of T cell receptor signalling by TCPTP

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/545845

Funding Status
Closed

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Funded Activity Summary

T cells play a central role in the immune response. The primary event in T cell activation is the triggering of a specific T cell receptor (TCR). Our studies will examine whether the protein TCPTP antagonises TCR-instigated T cell responses. Our studies may provide important new insights into alternative approaches for manipulating T cell-mediated immune responses in diseased states.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $317,076.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Clinical chemistry (incl. diagnostics)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Cell signalling | Immune regulation | Immunology | Protein tyrosine phosphatase | Signalling | Src-family tyrosine kinase | T cell immunity | T lymphocyte responses | T lymphocytes

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