Analysis and regulation of leptospiral virulence factors.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/545826

Funding Status
Closed

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Funded Activity Summary

Leptospirosis is a globally important infectious disease caused by Leptospira spp. This project aims to identify and characterise factors which play a role in disease development by knocking out genes, then investigating the impact on overall gene-protein expression in the mutant strain and its ability to cause disease. This will allow us to gain insights on mechanisms by which Leptospira spp. cause disease, leading to development of better methods of disease control and prevention.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $630,465.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Allergy

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

bacterial virulence factors | leptospirosis | microarray | molecular pathogenesis | mutation analysis | pathogenic mechanisms | proteomics | virulence

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