How amyloid causes neurodegeneration: the role of transthyretin in familial amyloidotic polyneuropathy

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/544920

Funding Status
Closed

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Funded Activity Summary

This project seeks to understand the biochemical basis of nerve degeneration in a disease known as familial amyloidotic polyneuropathy. This disease is caused by a protein known as transthyretin, which is abnormally deposited around nerves and causes nerve damage. The project is highly likely to provide clues which help us understand some related dementia causing diseases like Alzheimer's disease and prion diseases such as scrapie and mad cow disease.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $618,950.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cell Neurochemistry

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

calcium | ion channels | nervous system disorders | neuropathy | neurotoxicity | peripheral nerve injury | peripheral neuropathy | transthyretin

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