Mechanism of exacerbations in cystic fibrosis lung disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/544915

Funding Status
Closed

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Funded Activity Summary

Cystic Fibrosis lung disease is characterised by infeciton with a bug called Pseudomonas aeruginosa. Patients ultimately die in their mid-30's as a result of this infection, but lung decline is accelerated by episodes of exacerbation when patients cough up large volumes of mucky sputum. We are studying the casue of exacerbations by looking at bacterial behaviour and the response of the immune system. We will use this information to try and develop early warning signals and better treatments.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $254,876.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Allergy

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Airway inflammation | Cystic fibrosis | Pseudomonas aeruginosa | Pseudomonas aeruginosa infection | Virulence | bacterial virulence factors | health status | immune response

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