Adaptive changes in HIV-1 subtype C envelope glycoproteins contributing to pathogenicity.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/543133

Funding Status
Closed

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Funded Activity Summary

HIV exists as multiple subtypes. The most commonly studied is type B (B-HIV). B-HIV is common in North America, Europe and Asia, but accounts for only a small fraction of HIV infections worldwide. Type C HIV (C-HIV) in Africa and Asia accounts for the majority of infections worldwide, yet very little is known about how C-HIV causes AIDS. We aim to understand how C-HIV causes AIDS. This is critical for development of drugs and vaccines specifically designed for those who are most urgently need.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $427,648.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Applied immunology (incl. antibody engineering xenotransplantation and t-cell therapies)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

AIDS and immunodeficiency | Chemoreceptors | HIV pathogenesis | HIV-AIDS | Mechanism of human immunodeficiency virus infection | Molecular pathogenesis | Pathogenic mechanisms | Viral glycoproteins | Virus entry and replication

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