Biochemical and structural analysis of virus-host interactions during HIV-1 assembly

Funding Activity

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Funded Activity Summary

HIV Gag is the most important protein to direct the formation of infectious HIV. Researchers everywhere have had significant difficulty to generate full length HIV Gag for biochemical and structural analysis. We have since developed a novel way to prepare large amount of HIV Gag, and this project will take advantage of our discovery to determine the biochemical and the structural features of HIV Gag, ultimately, for the development of novel therapeutics through rational drug design.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $337,171.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Applied immunology (incl. antibody engineering xenotransplantation and t-cell therapies)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

HIV-AIDS | Infectious Diseases | Microbiology - Virology | protein interaction | virus formation | virus-host interplay