Wnt signalling in colon cancer

Funding Activity

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Funded Activity Summary

Colorectal cancer is a common malignancy in Australia and the mutation of one gene (Apc) is implicated in >80% of the cases. We aim to understand Apc biochemistry in normal and colon cancer cells by integrating mathematics with our experimental biology program. The main outcomes for this project will be a better understanding of the regulatory systems perturbed in colon cancer. We believe that the insights gained by our research will point the way to more effective treatments of colon cancer.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $550,725.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Protein Targeting And Signal Transduction

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

adenomas | colon cancer | colorectal cancer | computational modelling | irritable bowel disease | systems biology | tumour suppression | wnt signalling pathway