Discovery of long CD8+ T cell epitopes uncovers a hidden reservoir of immunodominant, anti-tumour responses

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/542508

Funding Status
Closed

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Funded Activity Summary

Stimulating killer T cells to eliminate tumours has been one of the ultimate yet elusive goals of cancer vaccine development. Vaccines aimed at stimulating killer T cells are similar to those generated under natural conditions. However, special strategies are needed to vaccinate beneficial killer T cells that are not normally part of the natural immunity. In this project, we will explore such a scenario and dissect the related mechanisms contributing to such differential immune outcomes.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $480,127.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Clinical chemistry (incl. diagnostics)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Immunity, cellular | T cell immunity | Vaccine development | X-ray crystallography | antigen presentation | cancer therapy | cancer vaccine | cell mediated immunity | structure | vaccine development

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