The characterisation of the glycolytic pathway and TCA cycle on first and second phase insulin secretion

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/535973

Funding Status
Closed

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Funded Activity Summary

In normal individuals, special cells in the pancreas - beta cells - secrete insulin. Insulin controls blood glucose. However, in diabetes, these beta cells have failed and are unable to perform their function, possibly due to faulty energy production. This project examines the underlying biochemical processes, in particular the energy requirements for insulin secretion. If we can repair this fault, it could identify novel targets for the treatment of diabetes.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2012

Funding Scheme: NHMRC Postgraduate Scholarships

Funding Amount: $85,716.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Nutritional science

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Diabetes mellitus | Gene knock-out | Glycolysis | Mitochondrial respiration

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