Dietary protein-induced DNA damage in colon and consequences for colorectal oncogenesis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/535079

Funding Status
Closed

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Funded Activity Summary

This research will explore the effects of dietary protein on genetic damage to cells lining the large bowel and risk of developing colorectal cancer. We will determine the degree and type of DNA damage resulting from increased protein, the cellular response to this DNA damage, whether it increases risk for developing bowel cancer and whether it can be minimised by other foods in both an animal model and humans.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $604,797.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

ANZSRC Socio-Economic Objective (SEO)

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Other Keywords

Colonic fermentation | Comet assay | DNA adducts | DNA repair | Dietary protein | High Protein diet | Red meat | chemoprevention | colorectal cancer risk | resistant starch

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