Gene therapy to improve corneal graft survival

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/535000

Funding Status
Closed

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Funded Activity Summary

The goal of our work is to improve outcomes for patients who are blind or seriously visually impaired as a result of corneal disease. Such patients can regain vision through a corneal transplant, but many such transplants fail. A corneal graft may fail because of an unwanted immune response, because blood vessels grow into the graft, or because some corneal cells die. We plan to transfer genes to the donor cornea in the laboratory, prior to corneal transplantation, to avoid such failure.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $514,048.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Opthalmology And Vision Science

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Blindness | Cornea | Corneal graft failure | Corneal scarring | Corneal transplantation | Gene therapy | Graft dysfunction | Lentiviral vector

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