Dissecting the contribution of malaria translocon components to pathogenesis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/533811

Funding Status
Closed

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Funded Activity Summary

The malaria parasite exports hundreds of proteins into its host red blood cell via a unique protein export machinery. This enables the parasite to avoid immune detection, resulting in over one million deaths annually. This proposal will use a rodent malaria infection model to address the functional significance and contribution of the machinery to malaria disease to discern if it will provide a potential target for anti-malaria drugs.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $326,583.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Humoural immunology and immunochemistry

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

animal model | malaria | molecular pathogenesis | pathogenicity of diseases | protein trafficking | protozoan parasitic disease | targeted gene disruption

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