A novel strategy targeting quorum sensing molecules and catalase function to block Pseudomonas aeruginosa lung infection

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/529309

Funding Status
Closed

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Funded Activity Summary

Pseudomonas aeruginosa causes serious infections, particularly in those with Cystic Fibrosis, immunocompromise, serious burns or long term catheters. We will use a unique strategy to target virulence factors that will assist in clearing acute infection, prevent establishment of new chronic infections, and potentially reduce severity of established chronic infections. It has the potential to make antibiotic therapy more effective and lessen the extent of antibiotic therapy required.

Funded Activity Details

Start Date: 01-01-2009

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $451,118.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Respiratory Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Chronic infection | Cystic fibrosis | Immunity to infection | Inflammation | host immune responses | pathogenesis of Pseudomonas aeruginosa | quorum sensing signal molecules | respiratory infection

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